Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKD All Species: 18.79
Human Site: T493 Identified Species: 41.33
UniProt: Q16760 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16760 NP_003639.2 1214 134525 T493 A H L S K I L T S D Q H S V V
Chimpanzee Pan troglodytes XP_001151474 1220 134870 E504 T K I L N S D E H A V V I S S
Rhesus Macaque Macaca mulatta XP_001114920 1167 129871 T449 A H L S K I L T S D Q H S V V
Dog Lupus familis XP_543293 1324 146248 T603 A H L S K I L T S D Q H S V V
Cat Felis silvestris
Mouse Mus musculus NP_808314 1220 135190 T493 A H L S K I L T S D Q H S V V
Rat Rattus norvegicus XP_347259 1196 133109 T473 A H L S K I L T S D Q H S V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507672 1254 138458 D534 L A K I L N S D Q H S V V I S
Chicken Gallus gallus XP_001232791 1333 149344 D611 L A K I L N S D Q H S V V I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693512 1148 127826 G438 V F D L M N G G P Q L G L R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A8JQ65 1895 211641 T525 F I V E T N D T Q T L I R S T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202627 1158 127377 L431 L N L L L Q T L K V E A Q A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.2 93.4 85.1 N.A. 93.7 90.2 N.A. 66.9 63.9 N.A. 60.9 N.A. 34.8 N.A. N.A. 53.3
Protein Similarity: 100 76.3 94.1 87.8 N.A. 96.4 93.3 N.A. 77.4 73.8 N.A. 71.6 N.A. 46.5 N.A. N.A. 65.8
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 0 0 N.A. 0 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 6.6 6.6 N.A. 6.6 N.A. 13.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 19 0 0 0 0 0 0 0 10 0 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 19 19 0 46 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 10 0 0 10 0 0 0 0 % E
% Phe: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 10 0 0 0 10 0 0 0 % G
% His: 0 46 0 0 0 0 0 0 10 19 0 46 0 0 0 % H
% Ile: 0 10 10 19 0 46 0 0 0 0 0 10 10 19 0 % I
% Lys: 0 10 19 0 46 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 28 0 55 28 28 0 46 10 0 0 19 0 10 0 10 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 10 37 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 28 10 46 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % R
% Ser: 0 0 0 46 0 10 19 0 46 0 19 0 46 19 28 % S
% Thr: 10 0 0 0 10 0 10 55 0 10 0 0 0 0 19 % T
% Val: 10 0 10 0 0 0 0 0 0 10 10 28 19 46 46 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _